Gilles de la Tourette syndrome is a condition that causes people to make repeated, quick movements or sounds that they cannot control. These movements or sounds are called tics.
The condition is commonly called Tourette syndrome.
See also:
Tourette syndrome
Tourette syndrome is named for Georges Gilles de la Tourette, who first described this disorder in 1885. There is strong evidence that Tourette syndrome is passed down through families, although the gene has not yet been found.
The syndrome may be linked to problems in certain areas of the brain. It may have to do with chemical substances (dopamine, serotonin, and norepinephrine) that help nerve cells talk to one another.
Tourette syndrome can be either severe or mild. About 10% of Americans have a mild tic disorder. Far fewer people have more severe forms of Tourette syndrome. Many people with very mild tics may not be aware of them and never seek medical help.
Tourette syndrome is four times as likely to occur in boys as in girls.
Most people with Tourette syndrome first notice symptoms during childhood, between ages 7 and 10.
The most common first symptom is a tic of the face, but other tics may follow. A tic is a sudden, fast, repeated movement or sound.
Symptoms of Tourette syndrome can range from tiny, minor movements (such as grunts, sniffling, or coughing) to constant movements and sounds that can't be controlled.
Tics can include:
Tics may occur many times a day, but they tend to improve or get worse at different times. The tics may change with time. Symptoms usually get worse before the mid-teen years.
Contrary to popular belief, only a small number of patients use curse words or other inappropriate words or phrases (coprolalia).
Tourette syndrome is different from obsessive-compulsive disorder (OCD). People with OCD feel as though they have to do the behaviors.
Many people with Tourette syndrome can stop doing the tic for periods of time. However, they find that the tic is stronger for a few minutes after they allow it to start again. Often the tic slows or stops during sleep.
There are no lab tests to diagnose Tourette syndrome. However, a health care provider should do an examination to rule out other causes of the symptoms.
To be diagnosed with Tourette syndrome, a person must:
Many patients with Tourette syndrome who have very minor symptoms are not treated, because the side effects of the medications may be worse than the symptoms of Tourette syndrome.
Drugs used to treat tics include:
Deep brain stimulation has shown promise for treating both the main symptoms of Tourette syndrome and the obsessive-compulsive behaviors, but not when these symptoms occur in the same person.
Tourette Syndrome Association - www.tsa-usa.org
Symptoms usually peak during the teenage years and then improve in early adulthood. Although 1 in 4 patients may be symptom-free for a few years, only 8% of symptoms go away without returning.
Patients usually have normal intelligence and live a normal-length life.
Conditions that may occur in people who have Tourette syndrome include:
These conditions need to be diagnosed and treated.
Make an appointment with your health care provider if you have tics that are severe or persistent, or if they interfere with your daily life.
There is no known prevention.
Gleason MM, Boris NW, Dalton R. Habit and tic disorders. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 23.
Jankovic J, Lang AE. Movement disorders: diagnosis and assessment. In: Bradley WG, Daroff RB, Fenichel GM, Jankovic J, eds. Neurology in Clinical Practice. 5th ed. Philadelphia, Pa: Butterworth-Heinemann Elsevier; 2008:chap 23.
Lang A. Other movement disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 434.
Kurlan R. Clinical practice Tourette's Syndrome. N Engl J Med. 2010;363(24):2332-2338.